Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 2' and Ligand = 'BDBM486357'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM486357 (US10947222, Example 2-A) Show SMILES Fc1ccc(cc1)-n1cc(-c2ccccc2Cl)c2ccc(cc12)C(=O)N[C@@H]1CCS(=O)(=O)C1 |r| Show InChI InChI=1S/C25H20ClFN2O3S/c26-23-4-2-1-3-20(23)22-14-29(19-8-6-17(27)7-9-19)24-13-16(5-10-21(22)24)25(30)28-18-11-12-33(31,32)15-18/h1-10,13-14,18H,11-12,15H2,(H,28,30)/t18-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	171	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US10947222 (2021) BindingDB Entry DOI: 10.7270/Q20P134X
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