Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 2' and Ligand = 'BDBM486407'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM486407 (N-(1,1-dioxidotetrahydrothiophen- 3-yl)-1-(4-fluor...) Show SMILES Fc1ccc(cc1)-n1cc(-c2cccc(c2)-n2cccn2)c2ccc(cc12)C(=O)NC1CCS(=O)(=O)C1 Show InChI InChI=1S/C28H23FN4O3S/c29-21-6-8-23(9-7-21)32-17-26(19-3-1-4-24(15-19)33-13-2-12-30-33)25-10-5-20(16-27(25)32)28(34)31-22-11-14-37(35,36)18-22/h1-10,12-13,15-17,22H,11,14,18H2,(H,31,34)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US10947222 (2021) BindingDB Entry DOI: 10.7270/Q20P134X
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