BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 2' and Ligand = 'BDBM486412'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Diacylglycerol O-acyltransferase 2


(Homo sapiens (Human))		BDBM486412
PNG
(3-[2-(difluoromethoxy)phenyl]-N- (1,1-dioxidotetra...)
Show SMILES FC(F)Oc1ccccc1-c1cn(-c2ccc(F)cc2)c2cc(ccc12)C(=O)NC1CCS(=O)(=O)C1
Show InChI InChI=1S/C26H21F3N2O4S/c27-17-6-8-19(9-7-17)31-14-22(21-3-1-2-4-24(21)35-26(28)29)20-10-5-16(13-23(20)31)25(32)30-18-11-12-36(33,34)15-18/h1-10,13-14,18,26H,11-12,15H2,(H,30,32)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 108n/an/an/an/an/an/a



Merck Sharp & Dohme Corp.

US Patent


Assay Description
DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...

US Patent US10947222 (2021)


BindingDB Entry DOI: 10.7270/Q20P134X
More data for this
Ligand-Target Pair