Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 2' and Ligand = 'BDBM530648'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM530648 (1-(5-(Difluoromethoxy)-2-fluorophenyl)-3-isopropyl...) Show SMILES CC(C)n1c2cc(ccc2n(-c2cc(OC(F)F)ccc2F)c1=O)C(=O)NC1(C)CCS(=O)(=O)CC1 |(.37,-5.69,;1.4,-4.54,;2.91,-4.86,;.92,-3.08,;-.54,-2.6,;-1.88,-3.37,;-3.21,-2.6,;-3.21,-1.06,;-1.88,-.29,;-.54,-1.06,;.92,-.59,;1.4,.88,;.37,2.02,;.85,3.49,;-.19,4.63,;-1.69,4.31,;-2.72,5.46,;-2.17,2.85,;2.35,3.81,;3.38,2.66,;2.91,1.2,;3.94,.05,;1.83,-1.83,;3.37,-1.83,;-4.54,-3.37,;-4.54,-4.91,;-5.88,-2.6,;-7.21,-3.37,;-7.21,-1.83,;-8.54,-2.6,;-9.88,-3.37,;-9.88,-4.91,;-11.21,-5.68,;-9.88,-6.45,;-8.54,-5.68,;-7.21,-4.91,)| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022076495	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...				Citation and Details BindingDB Entry DOI: 10.7270/Q2ZP4981
					More data for this Ligand-Target Pair