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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Diacylglycerol kinase zeta' and Ligand = 'BDBM594275'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Diacylglycerol kinase zeta


(Homo sapiens)
BDBM594275
PNG
(US11584747, Example 69 | US11584747, Example 70)
Show SMILES CC[C@@H]1CN([C@@H](C)CN1C(C)c1ccc(OCC2CC2)cc1F)c1nc(=O)n(C)c2ccc(nc12)C#N |r|
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 14n/an/an/an/an/an/a


TBA

Assay Description
The reactions were carried out in 50 mM MOPS pH 7.5, 100 mM NaCl, 10 mM MgCl2, 1 μM CaCl2, and 1 mM DTT (assay buffer). The reactions using a de...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z89HB5
More data for this
Ligand-Target Pair
Diacylglycerol kinase zeta


(Homo sapiens)
BDBM594275
PNG
(US11584747, Example 69 | US11584747, Example 70)
Show SMILES CC[C@@H]1CN([C@@H](C)CN1C(C)c1ccc(OCC2CC2)cc1F)c1nc(=O)n(C)c2ccc(nc12)C#N |r|
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.41E+3n/an/an/an/an/an/a


TBA

Assay Description
The reactions were carried out in 50 mM MOPS pH 7.5, 100 mM NaCl, 10 mM MgCl2, 1 μM CaCl2, and 1 mM DTT (assay buffer). The reactions using a de...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z89HB5
More data for this
Ligand-Target Pair