Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum) | BDBM120303 (US8703811, 42 | US8703811, 43) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 88 | n/a | n/a | n/a | n/a | n/a | n/a |
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College US Patent | Assay Description Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al... | US Patent US8703811 (2014) BindingDB Entry DOI: 10.7270/Q2WD3Z7P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum) | BDBM120303 (US8703811, 42 | US8703811, 43) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 104 | n/a | n/a | n/a | n/a | n/a | n/a |
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College US Patent | Assay Description Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al... | US Patent US8703811 (2014) BindingDB Entry DOI: 10.7270/Q2WD3Z7P | |||||||||||
More data for this Ligand-Target Pair |