Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dihydroorotate dehydrogenase (quinone), mitochondrial' and Ligand = 'BDBM50540322'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50540322 (CHEMBL4639767) Show SMILES Fc1ccccc1-n1ncc2[C@@H](CCCc12)NC(=O)c1ncccn1 |r| Show InChI InChI=1S/C18H16FN5O/c19-13-5-1-2-7-16(13)24-15-8-3-6-14(12(15)11-22-24)23-18(25)17-20-9-4-10-21-17/h1-2,4-5,7,9-11,14H,3,6,8H2,(H,23,25)/t14-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Karolinska Institutet Curated by ChEMBL					Assay Description Inhibition of recombinant human DHODH using dihydroorotic acid as substrate measured for 68 mins by DCIP based colorimetric assay				J Med Chem 63: 3915-3934 (2020) Article DOI: 10.1021/acs.jmedchem.9b01658 BindingDB Entry DOI: 10.7270/Q2HQ43F3
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