BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A]' and Ligand = 'BDBM9238'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A]


(Human immunodeficiency virus type 1)		BDBM9238
PNG
(acyclic urethane 13 | dec-9-en-1-yl N-[(2R,3S)-3-(...)
Show SMILES [H][C@@]1(CO[C@@]2([H])OCC[C@@]12[H])OC(=O)N[C@@H](Cc1ccccc1)[C@H](O)CN(CC=C)C(=O)OCCCCCCCCC=C |r|
Show InChI InChI=1S/C31H46N2O7/c1-3-5-6-7-8-9-10-14-19-38-31(36)33(18-4-2)22-27(34)26(21-24-15-12-11-13-16-24)32-30(35)40-28-23-39-29-25(28)17-20-37-29/h3-4,11-13,15-16,25-29,34H,1-2,5-10,14,17-23H2,(H,32,35)/t25-,26-,27+,28-,29+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3>-34.2n/an/an/an/an/a6.425



University of Illinois at Chicago



Assay Description
The Ki values were determined using fluorogenic substrate, 2-(aminobenzoyl)-Thr-Ile-Nle-Phe(p-NO2)-Gln-ArgNH2. A standard curve relating changes in f...

Bioorg Med Chem Lett 12: 1993-6 (2002)


Article DOI: 10.1016/s0960-894x(02)00300-1
BindingDB Entry DOI: 10.7270/Q2SJ1HS5
More data for this
Ligand-Target Pair