Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dimer of Protein farnesyltransferase subunit beta' and Ligand = 'BDBM50048971'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50048971 ((R)-2-({(S)-1-[(R)-2-((S)-2-Amino-3-mercapto-propy...) Show SMILES CSCC[C@@H](NC(=O)[C@@H]1CC=CCN1C(=O)[C@H](NC[C@H](N)CS)C(C)C)C(O)=O |c:10| Show InChI InChI=1S/C19H34N4O4S2/c1-12(2)16(21-10-13(20)11-28)18(25)23-8-5-4-6-15(23)17(24)22-14(19(26)27)7-9-29-3/h4-5,12-16,21,28H,6-11,20H2,1-3H3,(H,22,24)(H,26,27)/t13-,14+,15-,16+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibitory activity against Farnesyltransferase				J Med Chem 39: 224-36 (1996) Article DOI: 10.1021/jm950642a BindingDB Entry DOI: 10.7270/Q2610ZDS
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