Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Dimer of Protein farnesyltransferase subunit beta' and Ligand = 'BDBM50103323'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50103323 (4-(5-{[1-(3-Chloro-phenyl)-2-oxo-pyrrolidin-3-ylam...) Show SMILES Clc1cccc(c1)N1CC[C@H](NCc2cncn2Cc2ccc(cc2)C#N)C1=O Show InChI InChI=1S/C22H20ClN5O/c23-18-2-1-3-19(10-18)28-9-8-21(22(28)29)26-13-20-12-25-15-27(20)14-17-6-4-16(11-24)5-7-17/h1-7,10,12,15,21,26H,8-9,13-14H2/t21-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.40	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of farnesyl transferase using purified recombinant human enzyme				J Med Chem 44: 2933-49 (2001) BindingDB Entry DOI: 10.7270/Q2FF3RNW
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50103323 (4-(5-{[1-(3-Chloro-phenyl)-2-oxo-pyrrolidin-3-ylam...) Show SMILES Clc1cccc(c1)N1CC[C@H](NCc2cncn2Cc2ccc(cc2)C#N)C1=O Show InChI InChI=1S/C22H20ClN5O/c23-18-2-1-3-19(10-18)28-9-8-21(22(28)29)26-13-20-12-25-15-27(20)14-17-6-4-16(11-24)5-7-17/h1-7,10,12,15,21,26H,8-9,13-14H2/t21-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Concentration required to displace 50% of a potent radiolabeled FTI from farnesyl transferase in cultured H-ras-transformed Rat1 cells				J Med Chem 44: 2933-49 (2001) BindingDB Entry DOI: 10.7270/Q2FF3RNW
					More data for this Ligand-Target Pair