Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dimer of Protein farnesyltransferase subunit beta' and Ligand = 'BDBM50175406'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50175406 (CHEMBL200291 | N-((4-(4-cyanobenzyl)-4H-1,2,4-tria...) Show SMILES [O-][N+](=O)c1ccc(CN(Cc2nncn2Cc2ccc(cc2)C#N)C(=O)c2ccc3ccccc3n2)cc1 Show InChI InChI=1S/C28H21N7O3/c29-15-20-5-7-21(8-6-20)17-34-19-30-32-27(34)18-33(16-22-9-12-24(13-10-22)35(37)38)28(36)26-14-11-23-3-1-2-4-25(23)31-26/h1-14,19H,16-18H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research Foundation Curated by ChEMBL					Assay Description Inhibitory activity against K-Ras farnesyl transferase				Bioorg Med Chem Lett 15: 5407-11 (2005) Article DOI: 10.1016/j.bmcl.2005.09.007 BindingDB Entry DOI: 10.7270/Q2S18239
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