Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dimer of Protein farnesyltransferase subunit beta' and Ligand = 'BDBM50175408'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50175408 (CHEMBL371423 | N-(2,4-difluorobenzyl)-N-((4-((5-cy...) Show SMILES Fc1ccc(CN(Cc2nncn2Cc2ccc(cn2)C#N)C(=O)c2ccc3ccccc3n2)c(F)c1 Show InChI InChI=1S/C27H19F2N7O/c28-21-8-6-20(23(29)11-21)14-35(27(37)25-10-7-19-3-1-2-4-24(19)33-25)16-26-34-32-17-36(26)15-22-9-5-18(12-30)13-31-22/h1-11,13,17H,14-16H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research Foundation Curated by ChEMBL					Assay Description Inhibitory activity against K-Ras farnesyl transferase				Bioorg Med Chem Lett 15: 5407-11 (2005) Article DOI: 10.1016/j.bmcl.2005.09.007 BindingDB Entry DOI: 10.7270/Q2S18239
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