Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dimer of Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human)) | BDBM538618 (NCGC 00262327 | US11254667, Compound I-20 | US1154...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.508 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 8-10: Compounds were tested in 10-dose IC50 mode with 3-fold serial dilution starting at 10 uM, and are relative to DMSO, the negative control.... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MW8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human)) | BDBM538618 (NCGC 00262327 | US11254667, Compound I-20 | US1154...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 3 and 4: The HotSpot kinase profiling and screening assays were carried out using the method of Anastassiadis et al., Nat. Biotechnol. (2011) V... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MW8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human)) | BDBM538618 (NCGC 00262327 | US11254667, Compound I-20 | US1154...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 8-10: Compounds were tested in 10-dose IC50 mode with 3-fold serial dilution starting at 10 uM, and are relative to DMSO, the negative control.... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MW8 | |||||||||||
More data for this Ligand-Target Pair |