Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dipeptidyl peptidase 8 (Homo sapiens (Human)) | BDBM50339103![]() (5-Aminomethyl-4-(2,4-dichlorophenyl)-6-methyl-pyri...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of human recombinant DPP8 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before... | ACS Med Chem Lett 1: 530-535 (2010) Article DOI: 10.1021/ml100200c BindingDB Entry DOI: 10.7270/Q2513ZGH | |||||||||||
More data for this Ligand-Target Pair |