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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dipeptidyl peptidase 8' and Ligand = 'BDBM50516920'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dipeptidyl peptidase 8


(Homo sapiens (Human))		BDBM50516920
PNG
(CHEMBL4458949)
Show SMILES CC#CCn1c(nc2n(C)c(=O)n(Cc3c(Cl)cccc3C(O)=O)c(=O)c12)N1CCC[C@@H](N)C1 |r|
Show InChI InChI=1S/C23H25ClN6O4/c1-3-4-11-29-18-19(26-22(29)28-10-6-7-14(25)12-28)27(2)23(34)30(20(18)31)13-16-15(21(32)33)8-5-9-17(16)24/h5,8-9,14H,6-7,10-13,25H2,1-2H3,(H,32,33)/t14-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Guangxi Medical University

Curated by ChEMBL


Assay Description
Inhibition of DPP8 (unknown origin) using Gly-Pro-AMC as substrate preincubated for 15 mins followed by substrate addition measured at 60 secs interv...

Eur J Med Chem 180: 509-523 (2019)


Article DOI: 10.1016/j.ejmech.2019.07.045
BindingDB Entry DOI: 10.7270/Q2Q243MN
More data for this
Ligand-Target Pair