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Found 1 hit Enz. Inhib. hit(s) with Target = 'Dipeptidyl peptidase 8' and Ligand = 'BDBM50516923'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dipeptidyl peptidase 8


(Homo sapiens (Human))		BDBM50516923
PNG
(CHEMBL4590999)
Show SMILES COC(=O)c1c(F)cccc1Cn1c(=O)n(C)c2nc(N3CCC[C@@H](N)C3)n(CC#CC)c2c1=O |r|
Show InChI InChI=1S/C24H27FN6O4/c1-4-5-12-30-19-20(27-23(30)29-11-7-9-16(26)14-29)28(2)24(34)31(21(19)32)13-15-8-6-10-17(25)18(15)22(33)35-3/h6,8,10,16H,7,9,11-14,26H2,1-3H3/t16-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Guangxi Medical University

Curated by ChEMBL


Assay Description
Inhibition of DPP8 (unknown origin) using Gly-Pro-AMC as substrate preincubated for 15 mins followed by substrate addition measured at 60 secs interv...

Eur J Med Chem 180: 509-523 (2019)


Article DOI: 10.1016/j.ejmech.2019.07.045
BindingDB Entry DOI: 10.7270/Q2Q243MN
More data for this
Ligand-Target Pair