Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Disintegrin and metalloproteinase domain-containing protein 17' and Ligand = 'BDBM26802'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Disintegrin and metalloproteinase domain-containing protein 17 (Sus scrofa (pig))	BDBM26802 ((5R,7R,8S)-7-N-(4-{[2-(2-fluoropropan-2-yl)-1H-1,3...) Show SMILES CC(C)(F)c1nc2ccccc2n1Cc1ccc(cc1)C(=O)N[C@@H]1C[C@@]2(CCCO2)C[C@@H]1C(=O)NO |r| Show InChI InChI=1S/C27H31FN4O4/c1-26(2,28)25-30-20-6-3-4-7-22(20)32(25)16-17-8-10-18(11-9-17)23(33)29-21-15-27(12-5-13-36-27)14-19(21)24(34)31-35/h3-4,6-11,19,21,35H,5,12-16H2,1-2H3,(H,29,33)(H,31,34)/t19-,21+,27+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<1	n/a	n/a	n/a	n/a	7.5	25
Bristol-Myers Squibb Company					Assay Description The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...				Bioorg Med Chem Lett 18: 1577-82 (2008) Article DOI: 10.1016/j.bmcl.2008.01.075 BindingDB Entry DOI: 10.7270/Q2GM85NS
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