Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Disintegrin and metalloproteinase domain-containing protein 17' and Ligand = 'BDBM50103166'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50103166 (5-Bromo-N-hydroxy-3-methyl-2-{methyl-[4'-(pyridin-...) Show SMILES CN(c1c(C)cc(Br)cc1C(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccc(OCc2cccnc2)cc1 Show InChI InChI=1S/C27H24BrN3O5S/c1-18-14-22(28)15-25(27(32)30-33)26(18)31(2)37(34,35)24-11-7-21(8-12-24)20-5-9-23(10-6-20)36-17-19-4-3-13-29-16-19/h3-16,33H,17H2,1-2H3,(H,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro inhibition of TNF-alpha converting enzyme (TACE)				Bioorg Med Chem Lett 11: 2189-92 (2001) BindingDB Entry DOI: 10.7270/Q2154HK0
					More data for this Ligand-Target Pair