Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Disintegrin and metalloproteinase domain-containing protein 17' and Ligand = 'BDBM50325020'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50325020 ((+/-)-5-((6-fluoro-1-oxoisoindolin-2-yl)methyl)-5-...) Show SMILES Fc1ccc2CN(CC3(NC(=O)NC3=O)c3cccc(Oc4ccccc4)c3)C(=O)c2c1 Show InChI InChI=1S/C24H18FN3O4/c25-17-10-9-15-13-28(21(29)20(15)12-17)14-24(22(30)26-23(31)27-24)16-5-4-8-19(11-16)32-18-6-2-1-3-7-18/h1-12H,13-14H2,(H2,26,27,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of TACE assessed as inhibition of pro-TNFalpha peptide cleavage				Bioorg Med Chem Lett 20: 5286-9 (2010) Article DOI: 10.1016/j.bmcl.2010.06.134 BindingDB Entry DOI: 10.7270/Q26W9B8K
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