Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Dopamine beta-hydroxylase' and Ligand = 'BDBM50025784'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dopamine beta-hydroxylase (Rattus norvegicus)	BDBM50025784 (1-(4-Methoxy-3-nitro-benzyl)-1,3-dihydro-imidazole...) Show SMILES COc1ccc(Cn2cc[nH]c2=S)cc1[N+]([O-])=O Show InChI InChI=1S/C11H11N3O3S/c1-17-10-3-2-8(6-9(10)14(15)16)7-13-5-4-12-11(13)18/h2-6H,7H2,1H3,(H,12,18)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.55E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois Curated by ChEMBL					Assay Description Inhibition of dopamine beta-hydroxylase (DbetaH) in hypertensive rats when administered orally (or) intraperitoneally				J Med Chem 33: 274-81 (1990) BindingDB Entry DOI: 10.7270/Q26Q1ZD2
					More data for this Ligand-Target Pair
Dopamine beta-hydroxylase (Homo sapiens (Human))	BDBM50025784 (1-(4-Methoxy-3-nitro-benzyl)-1,3-dihydro-imidazole...) Show SMILES COc1ccc(Cn2cc[nH]c2=S)cc1[N+]([O-])=O Show InChI InChI=1S/C11H11N3O3S/c1-17-10-3-2-8(6-9(10)14(15)16)7-13-5-4-12-11(13)18/h2-6H,7H2,1H3,(H,12,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.55E+5	n/a	n/a	n/a	n/a	n/a	n/a
Molecular Simulations Inc Curated by ChEMBL					Assay Description Inhibition of dopamine beta hydroxylase				J Med Chem 38: 2091-102 (1995) BindingDB Entry DOI: 10.7270/Q2W37XH8
					More data for this Ligand-Target Pair
Dopamine beta-hydroxylase (Homo sapiens (Human))	BDBM50025784 (1-(4-Methoxy-3-nitro-benzyl)-1,3-dihydro-imidazole...) Show SMILES COc1ccc(Cn2cc[nH]c2=S)cc1[N+]([O-])=O Show InChI InChI=1S/C11H11N3O3S/c1-17-10-3-2-8(6-9(10)14(15)16)7-13-5-4-12-11(13)18/h2-6H,7H2,1H3,(H,12,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.55E+5	n/a	n/a	n/a	n/a	n/a	n/a
Harvard University Curated by ChEMBL					Assay Description Inhibition of dopamine beta-hydroxylase (DbetaH) enzyme				J Med Chem 40: 4360-71 (1998) Article DOI: 10.1021/jm970488n BindingDB Entry DOI: 10.7270/Q2BZ6784
					More data for this Ligand-Target Pair
Dopamine beta-hydroxylase (Bos taurus)	BDBM50025784 (1-(4-Methoxy-3-nitro-benzyl)-1,3-dihydro-imidazole...) Show SMILES COc1ccc(Cn2cc[nH]c2=S)cc1[N+]([O-])=O Show InChI InChI=1S/C11H11N3O3S/c1-17-10-3-2-8(6-9(10)14(15)16)7-13-5-4-12-11(13)18/h2-6H,7H2,1H3,(H,12,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.59E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory Concentration against bovine Dopamine beta hydroxylase (DBH);Range is between (230-606).				J Med Chem 30: 486-94 (1987) BindingDB Entry DOI: 10.7270/Q2FJ2FSM
					More data for this Ligand-Target Pair