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Found 1 hit Enz. Inhib. hit(s) with Target = 'Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A' and Ligand = 'BDBM50467479'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A


(Homo sapiens (Human))		BDBM50467479
PNG
(CHEMBL4281081)
Show SMILES [H][C@]12Cc3c([nH]c4ccccc34)[C@H](N1C(=O)N(CC)C2=O)c1ccc(CC)s1 |r|
Show InChI InChI=1S/C21H21N3O2S/c1-3-12-9-10-17(27-12)19-18-14(13-7-5-6-8-15(13)22-18)11-16-20(25)23(4-2)21(26)24(16)19/h5-10,16,19,22H,3-4,11H2,1-2H3/t16-,19-/m1/s1
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 169n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of full length recombinant human N-terminal GST-tagged PDE11A4 expressed in baculovirus infected sf9 cells using FAM-cyclic-3',5-AMP as su...

Eur J Med Chem 158: 767-780 (2018)


Article DOI: 10.1016/j.ejmech.2018.09.028
BindingDB Entry DOI: 10.7270/Q2JS9T4N
More data for this
Ligand-Target Pair