Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dual specificity mitogen-activated protein kinase kinase 1' and Ligand = 'BDBM50176602'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity mitogen-activated protein kinase kinase 1 (Homo sapiens (Human))	BDBM50176602 (CHEMBL371969 | ethyl 3-cyano-5-(ethoxymethyl)-4-(4...) Show SMILES CCOCc1c(cn2ncc(C#N)c(Nc3ccc(Oc4ccccc4)cc3)c12)C(=O)OCC Show InChI InChI=1S/C26H24N4O4/c1-3-32-17-23-22(26(31)33-4-2)16-30-25(23)24(18(14-27)15-28-30)29-19-10-12-21(13-11-19)34-20-8-6-5-7-9-20/h5-13,15-16,29H,3-4,17H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	331	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against MEK				Bioorg Med Chem Lett 16: 628-32 (2005) Article DOI: 10.1016/j.bmcl.2005.10.052 BindingDB Entry DOI: 10.7270/Q2J67GHT
					More data for this Ligand-Target Pair