Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dual specificity protein kinase TTK/Glutathione S-transferase P' and Ligand = 'BDBM259479'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity protein kinase TTK/Glutathione S-transferase P (Homo sapiens (Human))	BDBM259479 (US9512126, 20) Show SMILES Cc1cc(ccc1C(=O)NC1CC1)-c1cnc2c(NCCC(F)(F)F)cc(nn12)C1(CC1)c1cc(F)ccc1F Show InChI InChI=1S/C29H26F5N5O/c1-16-12-17(2-6-20(16)27(40)37-19-4-5-19)24-15-36-26-23(35-11-10-29(32,33)34)14-25(38-39(24)26)28(8-9-28)21-13-18(30)3-7-22(21)31/h2-3,6-7,12-15,19,35H,4-5,8-11H2,1H3,(H,37,40)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	7.7	22
Bayer Intellectual Property GmbH US Patent					Assay Description The human kinase Mps-1 phosphorylates a biotinylated substrate peptide. Detection of the phosphorylated product is achieved by time-resolved fluoresc...				US Patent US9512126 (2016) BindingDB Entry DOI: 10.7270/Q2Q23Z5S
					More data for this Ligand-Target Pair