Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Dual specificity tyrosine-phosphorylation-regulated kinase 1A' and Ligand = 'BDBM442821'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM442821 (US10653688, Compound 10 | US10653688, Compound 151...) Show SMILES O=C(CN1CCOCC1)Nc1cc2cc(ccc2cn1)-c1cccnc1 Show InChI InChI=1S/C20H20N4O2/c25-20(14-24-6-8-26-9-7-24)23-19-11-18-10-15(3-4-17(18)13-22-19)16-2-1-5-21-12-16/h1-5,10-13H,6-9,14H2,(H,22,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	9	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The DYRK1A kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Divis...				US Patent US10653688 (2020) BindingDB Entry DOI: 10.7270/Q2Z322PW
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM442821 (US10653688, Compound 10 | US10653688, Compound 151...) Show SMILES O=C(CN1CCOCC1)Nc1cc2cc(ccc2cn1)-c1cccnc1 Show InChI InChI=1S/C20H20N4O2/c25-20(14-24-6-8-26-9-7-24)23-19-11-18-10-15(3-4-17(18)13-22-19)16-2-1-5-21-12-16/h1-5,10-13H,6-9,14H2,(H,22,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The DYRK1A kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Divis...				US Patent US10653688 (2020) BindingDB Entry DOI: 10.7270/Q2Z322PW
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM442821 (US10653688, Compound 10 | US10653688, Compound 151...) Show SMILES O=C(CN1CCOCC1)Nc1cc2cc(ccc2cn1)-c1cccnc1 Show InChI InChI=1S/C20H20N4O2/c25-20(14-24-6-8-26-9-7-24)23-19-11-18-10-15(3-4-17(18)13-22-19)16-2-1-5-21-12-16/h1-5,10-13H,6-9,14H2,(H,22,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The DYRK1A kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Divis...				US Patent US10653688 (2020) BindingDB Entry DOI: 10.7270/Q2Z322PW
					More data for this Ligand-Target Pair