Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dual specificity tyrosine-phosphorylation-regulated kinase 1A' and Ligand = 'BDBM442877'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM442877 (US10653688, Compound 59) Show SMILES CNC(=O)c1cncc(c1)-c1ccc2cnc(NC(=O)c3ccnc(c3)N3CCN(C)CC3)cc2c1 Show InChI InChI=1S/C27H27N7O2/c1-28-26(35)23-12-22(15-29-16-23)18-3-4-20-17-31-24(13-21(20)11-18)32-27(36)19-5-6-30-25(14-19)34-9-7-33(2)8-10-34/h3-6,11-17H,7-10H2,1-2H3,(H,28,35)(H,31,32,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	6	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The DYRK1A kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Divis...				US Patent US10653688 (2020) BindingDB Entry DOI: 10.7270/Q2Z322PW
					More data for this Ligand-Target Pair