Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Dual specificity tyrosine-phosphorylation-regulated kinase 1A' and Ligand = 'BDBM484692'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM484692 (US10934297, Compound 85 | US11713320, Compound 85) Show SMILES CN1Cc2ccc(NC(=O)c3n[nH]c4cc(F)c(cc34)-c3cnn(C)c3)cc2C1 Show InChI InChI=1S/C21H19FN6O/c1-27-9-12-3-4-15(5-13(12)10-27)24-21(29)20-17-6-16(14-8-23-28(2)11-14)18(22)7-19(17)25-26-20/h3-8,11H,9-10H2,1-2H3,(H,24,29)(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q20P144B
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM484692 (US10934297, Compound 85 | US11713320, Compound 85) Show SMILES CN1Cc2ccc(NC(=O)c3n[nH]c4cc(F)c(cc34)-c3cnn(C)c3)cc2C1 Show InChI InChI=1S/C21H19FN6O/c1-27-9-12-3-4-15(5-13(12)10-27)24-21(29)20-17-6-16(14-8-23-28(2)11-14)18(22)7-19(17)25-26-20/h3-8,11H,9-10H2,1-2H3,(H,24,29)(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description DYRK1A: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 11-point dose-response...				US Patent US10934297 (2021) BindingDB Entry DOI: 10.7270/Q23N26GM
					More data for this Ligand-Target Pair