Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dual specificity tyrosine-phosphorylation-regulated kinase 1A' and Ligand = 'BDBM50114577'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50114577 (CHEMBL3609566) Show SMILES [H][C@@]12C[C@@H](CCN1C(=O)c1cccc(NC(=O)Nc3ccccn3)c21)OC |r| Show InChI InChI=1S/C19H20N4O3/c1-26-12-8-10-23-15(11-12)17-13(18(23)24)5-4-6-14(17)21-19(25)22-16-7-2-3-9-20-16/h2-7,9,12,15H,8,10-11H2,1H3,(H2,20,21,22,25)/t12-,15+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR 7311 Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-tagged DYRK1A expressed in Escherichia coli				Eur J Med Chem 101: 274-87 (2015) Article DOI: 10.1016/j.ejmech.2015.06.046 BindingDB Entry DOI: 10.7270/Q24T6M53
					More data for this Ligand-Target Pair