Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dual specificity tyrosine-phosphorylation-regulated kinase 1A' and Ligand = 'BDBM50114787'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50114787 (CHEMBL3609744) Show SMILES [H][C@@]12C[C@@H](CCN1C(=O)c1cccc(NC(=O)Nc3cc(C)ccn3)c21)OC |r| Show InChI InChI=1S/C20H22N4O3/c1-12-6-8-21-17(10-12)23-20(26)22-15-5-3-4-14-18(15)16-11-13(27-2)7-9-24(16)19(14)25/h3-6,8,10,13,16H,7,9,11H2,1-2H3,(H2,21,22,23,26)/t13-,16+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR 7311 Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-tagged DYRK1A expressed in Escherichia coli				Eur J Med Chem 101: 274-87 (2015) Article DOI: 10.1016/j.ejmech.2015.06.046 BindingDB Entry DOI: 10.7270/Q24T6M53
					More data for this Ligand-Target Pair