Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human)) | BDBM50581214 (CHEMBL5078833) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of DYRK1A (unknown origin) by TR FRET assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human)) | BDBM50581214 (CHEMBL5078833) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of DYRK1A (unknown origin) assessed as accumulation of ADP by ADP hunter plus assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human)) | BDBM50581214 (CHEMBL5078833) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of DYRK1A expressed in human U2OS cells assessed as reduction in autophosphorylation at S520 residue incubated for 5 hrs | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 | |||||||||||
More data for this Ligand-Target Pair |