Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase Mdm2' and Ligand = 'BDBM50513208'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM50513208 (CHEMBL4539441) Show SMILES CC(=O)N1C(=O)[C@@]2(S[C@H]([C@@H](O)C[C@@H]2c2ccccc2)C(=O)c2ccccc2)c2c1cccc2Br |r| Show InChI InChI=1S/C27H22BrNO4S/c1-16(30)29-21-14-8-13-20(28)23(21)27(26(29)33)19(17-9-4-2-5-10-17)15-22(31)25(34-27)24(32)18-11-6-3-7-12-18/h2-14,19,22,25,31H,15H2,1H3/t19-,22+,25-,27+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	9.68E+3	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Binding affinity to MDM2 (unknown origin) by fluorescence polarization assay				Eur J Med Chem 176: 92-104 (2019) Article DOI: 10.1016/j.ejmech.2019.05.018 BindingDB Entry DOI: 10.7270/Q2V12851
					More data for this Ligand-Target Pair