Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase Mdm2' and Ligand = 'BDBM50513210'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM50513210 (CHEMBL4548943) Show SMILES O[C@H]1C[C@H](c2ccccc2)[C@@]2(S[C@H]1C(=O)c1ccc(Br)cc1)C(=O)Nc1cccc(Br)c21 |r| Show InChI InChI=1S/C25H19Br2NO3S/c26-16-11-9-15(10-12-16)22(30)23-20(29)13-17(14-5-2-1-3-6-14)25(32-23)21-18(27)7-4-8-19(21)28-24(25)31/h1-12,17,20,23,29H,13H2,(H,28,31)/t17-,20+,23-,25+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	6.36E+3	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Binding affinity to MDM2 (unknown origin) by fluorescence polarization assay				Eur J Med Chem 176: 92-104 (2019) Article DOI: 10.1016/j.ejmech.2019.05.018 BindingDB Entry DOI: 10.7270/Q2V12851
					More data for this Ligand-Target Pair