BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'EH domain-containing protein 1' and Ligand = 'BDBM50453866'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
EH domain-containing protein 1


(Homo sapiens)		BDBM50453866
PNG
(CHEMBL4210684)
Show SMILES NC(=O)C[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSCc2ccccc2CSCCNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CCCN2C1=O)NC(=O)CCC#C |r|
Show InChI InChI=1S/C50H60N8O11S2/c1-2-3-15-43(61)53-40-30-71-29-34-13-8-7-12-33(34)28-70-24-22-52-45(64)36(20-21-44(62)63)54-46(65)38(25-31-10-5-4-6-11-31)56-49(68)41-14-9-23-58(41)50(69)39(27-42(51)60)57-47(66)37(55-48(40)67)26-32-16-18-35(59)19-17-32/h1,4-8,10-13,16-19,36-41,59H,3,9,14-15,20-30H2,(H2,51,60)(H,52,64)(H,53,61)(H,54,65)(H,55,67)(H,56,68)(H,57,66)(H,62,63)/t36-,37-,38-,39-,40-,41-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 7.65E+4n/an/an/an/an/an/a



Tufts University

Curated by ChEMBL


Assay Description
Inhibition of fluorescence-labelled cNPF1 probe binding to GST-fused EHD1 EH domain (unknown origin) expressed in Escherichia coli BL21 cells pretrea...

Bioorg Med Chem 26: 1206-1211 (2018)


Article DOI: 10.1016/j.bmc.2017.09.007
BindingDB Entry DOI: 10.7270/Q2CN76G0
More data for this
Ligand-Target Pair