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Found 1 hit Enz. Inhib. hit(s) with Target = 'Ectonucleotide pyrophosphatase/phosphodiesterase family member 2' and Ligand = 'BDBM50542069'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2


(Homo sapiens (Human))		BDBM50542069
PNG
(CHEMBL4649090)
Show SMILES CC(C)(CCC(=O)N1CCc2c(C1)n(Cc1cccc(F)c1)c1ncccc21)CC(O)=O
Show InChI InChI=1S/C25H28FN3O3/c1-25(2,14-23(31)32)10-8-22(30)28-12-9-19-20-7-4-11-27-24(20)29(21(19)16-28)15-17-5-3-6-18(26)13-17/h3-7,11,13H,8-10,12,14-16H2,1-2H3,(H,31,32)
PDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 24n/an/an/an/an/an/a



Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of recombinant human ATX assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrs

ACS Med Chem Lett 11: 1335-1341 (2020)


Article DOI: 10.1021/acsmedchemlett.0c00200
BindingDB Entry DOI: 10.7270/Q2DB85D8
More data for this
Ligand-Target Pair