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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Egl nine homolog 1' and Ligand = 'BDBM50320450'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Egl nine homolog 1


(Homo sapiens (Human))		BDBM50320450
PNG
(CHEMBL4169295)
Show SMILES OC(=O)CNC(=O)c1c(O)c2CNCCc2n(Cc2ccc(cc2)C(F)(F)F)c1=O
Show InChI InChI=1S/C19H18F3N3O5/c20-19(21,22)11-3-1-10(2-4-11)9-25-13-5-6-23-7-12(13)16(28)15(18(25)30)17(29)24-8-14(26)27/h1-4,23,28H,5-9H2,(H,24,29)(H,26,27)
PDB
MMDB

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n/an/a 23n/an/an/an/an/an/a



Cadila Healthcare Limited

Curated by ChEMBL


Assay Description
Inhibition of FLAG- tagged full length HIF-PHD2 (unknown origin) expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQ...

J Med Chem 61: 6964-6982 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01686
BindingDB Entry DOI: 10.7270/Q2H70JC7
More data for this
Ligand-Target Pair