BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Egl nine homolog 1' and Ligand = 'BDBM50321026'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Egl nine homolog 1


(Homo sapiens (Human))		BDBM50321026
PNG
(CHEMBL4172984)
Show SMILES OC(=O)CNC(=O)c1c(O)c2CCCCc2n(Cc2ccc(cc2)C(F)(F)F)c1=O
Show InChI InChI=1S/C20H19F3N2O5/c21-20(22,23)12-7-5-11(6-8-12)10-25-14-4-2-1-3-13(14)17(28)16(19(25)30)18(29)24-9-15(26)27/h5-8,28H,1-4,9-10H2,(H,24,29)(H,26,27)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 66n/an/an/an/an/an/a



Cadila Healthcare Limited

Curated by ChEMBL


Assay Description
Inhibition of FLAG- tagged full length HIF-PHD2 (unknown origin) expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQ...

J Med Chem 61: 6964-6982 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01686
BindingDB Entry DOI: 10.7270/Q2H70JC7
More data for this
Ligand-Target Pair