Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Egl nine homolog 1 [181-417]' and Ligand = 'BDBM475428'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475428 (1-(6-Chloro-5-nitro-1H-benzoimidazol-2-yl)-1H-pyra...) Show SMILES OC(=O)c1cnn(c1)-c1nc2cc(c(Cl)cc2[nH]1)[N+]([O-])=O Show InChI InChI=1S/C11H6ClN5O4/c12-6-1-7-8(2-9(6)17(20)21)15-11(14-7)16-4-5(3-13-16)10(18)19/h1-4H,(H,14,15)(H,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31.6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V69PHV
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475428 (1-(6-Chloro-5-nitro-1H-benzoimidazol-2-yl)-1H-pyra...) Show SMILES OC(=O)c1cnn(c1)-c1nc2cc(c(Cl)cc2[nH]1)[N+]([O-])=O Show InChI InChI=1S/C11H6ClN5O4/c12-6-1-7-8(2-9(6)17(20)21)15-11(14-7)16-4-5(3-13-16)10(18)19/h1-4H,(H,14,15)(H,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31.6	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...				US Patent US10851083 (2020) BindingDB Entry DOI: 10.7270/Q25B05K9
					More data for this Ligand-Target Pair