Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Egl nine homolog 1 [181-417]' and Ligand = 'BDBM475470'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475470 (1-[6-Chloro-5-(toluene-3-sulfonyl)-1H-benzoimidazo...) Show SMILES Cc1cccc(c1)S(=O)(=O)c1cc2nc([nH]c2cc1Cl)-n1cc(cn1)C(O)=O Show InChI InChI=1S/C18H13ClN4O4S/c1-10-3-2-4-12(5-10)28(26,27)16-7-15-14(6-13(16)19)21-18(22-15)23-9-11(8-20-23)17(24)25/h2-9H,1H3,(H,21,22)(H,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	39.8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V69PHV
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475470 (1-[6-Chloro-5-(toluene-3-sulfonyl)-1H-benzoimidazo...) Show SMILES Cc1cccc(c1)S(=O)(=O)c1cc2nc([nH]c2cc1Cl)-n1cc(cn1)C(O)=O Show InChI InChI=1S/C18H13ClN4O4S/c1-10-3-2-4-12(5-10)28(26,27)16-7-15-14(6-13(16)19)21-18(22-15)23-9-11(8-20-23)17(24)25/h2-9H,1H3,(H,21,22)(H,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	39.8	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...				US Patent US10851083 (2020) BindingDB Entry DOI: 10.7270/Q25B05K9
					More data for this Ligand-Target Pair