Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Egl nine homolog 1 [181-417]' and Ligand = 'BDBM475491'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475491 (1-[6-(Propane-2-sulfonyl)-5-trifluoromethyl-1H- | ...) Show SMILES CC(C)S(=O)(=O)c1cc2[nH]c(nc2cc1C(F)(F)F)-n1cc(cn1)C(O)=O Show InChI InChI=1S/C15H13F3N4O4S/c1-7(2)27(25,26)12-4-11-10(3-9(12)15(16,17)18)20-14(21-11)22-6-8(5-19-22)13(23)24/h3-7H,1-2H3,(H,20,21)(H,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	39.8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V69PHV
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475491 (1-[6-(Propane-2-sulfonyl)-5-trifluoromethyl-1H- | ...) Show SMILES CC(C)S(=O)(=O)c1cc2[nH]c(nc2cc1C(F)(F)F)-n1cc(cn1)C(O)=O Show InChI InChI=1S/C15H13F3N4O4S/c1-7(2)27(25,26)12-4-11-10(3-9(12)15(16,17)18)20-14(21-11)22-6-8(5-19-22)13(23)24/h3-7H,1-2H3,(H,20,21)(H,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	39.8	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...				US Patent US10851083 (2020) BindingDB Entry DOI: 10.7270/Q25B05K9
					More data for this Ligand-Target Pair