Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Egl nine homolog 1 [181-417]' and Ligand = 'BDBM475548'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475548 (1-[5-(4-Methoxy-phenylsulfanyl)-6-trifluoromethyl-...) Show SMILES COc1ccc(Sc2cc3nc([nH]c3cc2C(F)(F)F)-n2cc(cn2)C(O)=O)cc1 Show InChI InChI=1S/C19H13F3N4O3S/c1-29-11-2-4-12(5-3-11)30-16-7-15-14(6-13(16)19(20,21)22)24-18(25-15)26-9-10(8-23-26)17(27)28/h2-9H,1H3,(H,24,25)(H,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31.6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V69PHV
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475548 (1-[5-(4-Methoxy-phenylsulfanyl)-6-trifluoromethyl-...) Show SMILES COc1ccc(Sc2cc3nc([nH]c3cc2C(F)(F)F)-n2cc(cn2)C(O)=O)cc1 Show InChI InChI=1S/C19H13F3N4O3S/c1-29-11-2-4-12(5-3-11)30-16-7-15-14(6-13(16)19(20,21)22)24-18(25-15)26-9-10(8-23-26)17(27)28/h2-9H,1H3,(H,24,25)(H,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31.6	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...				US Patent US10851083 (2020) BindingDB Entry DOI: 10.7270/Q25B05K9
					More data for this Ligand-Target Pair