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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Elongin-B/Elongin-C [17-112]/von Hippel-Lindau disease tumor suppressor [55-213]' and Ligand = 'BDBM536209'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Elongin-B/Elongin-C [17-112]/von Hippel-Lindau disease tumor suppressor [55-213]


(Homo sapiens (Human))
BDBM536209
PNG
((R)-1-((2S,4R)-4-hydroxy-2-(1-oxa-2,4-diazaspiro[4...)
Show SMILES CC(C)[C@@H](C(=O)N1C[C@H](O)C[C@H]1C1=NOC2(CCCC2)N1)c1cc(C)no1 |r,t:13|
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.08E+4n/an/an/an/an/an/a


TBA

Assay Description
The binding of test compounds to the VHL Elongin B/C complex was measured using a fluorescence polarization tracer competition assay. The VHL/Elongin...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2KW5K7X
More data for this
Ligand-Target Pair
Elongin-B/Elongin-C [17-112]/von Hippel-Lindau disease tumor suppressor [55-213]


(Homo sapiens (Human))
BDBM536209
PNG
((R)-1-((2S,4R)-4-hydroxy-2-(1-oxa-2,4-diazaspiro[4...)
Show SMILES CC(C)[C@@H](C(=O)N1C[C@H](O)C[C@H]1C1=NOC2(CCCC2)N1)c1cc(C)no1 |r,t:13|
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/a 1.64E+4n/an/an/an/an/a


TBA

Assay Description
Using a Biacore T200, Avidin tagged VHL co-expressed with Elongins B and C were immobilized to a Biacore SA chip in running buffer without DMSO. Comp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2KW5K7X
More data for this
Ligand-Target Pair