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Found 1 hit Enz. Inhib. hit(s) with Target = 'Elongin-B/Elongin-C [17-112]/von Hippel-Lindau disease tumor suppressor [55-213]' and Ligand = 'BDBM536291'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Elongin-B/Elongin-C [17-112]/von Hippel-Lindau disease tumor suppressor [55-213]


(Homo sapiens (Human))		BDBM536291
PNG
((5S)-2-((4R)-1-(2-(3-((6-(2-((4-((3-Ethynylphenyl)...)
Show SMILES COCCOc1cc2ncnc(Nc3cccc(c3)C#C)c2cc1OCCOCC#CC#CCOc1cc(on1)[C@@H](C(C)C)C(=O)N1C[C@H](O)C[C@H]1C1=NC(=O)[C@@](C)(N1)c1ccc(cc1)-c1scnc1C |r,t:57|
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 6.25E+3n/an/an/an/an/an/a


TBA

Assay Description
The binding of test compounds to the VHL Elongin B/C complex was measured using a fluorescence polarization tracer competition assay. The VHL/Elongin...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KW5K7X
More data for this
Ligand-Target Pair