Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Endoplasmic reticulum aminopeptidase 1' and Ligand = 'BDBM50519954'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endoplasmic reticulum aminopeptidase 1 (Homo sapiens (Human))	BDBM50519954 (CHEMBL4434818) Show SMILES Cc1ccc(NC(=N)NC2(CCCCC2)C(=O)N2CCN(CC2)c2ccccc2)cc1 Show InChI InChI=1S/C25H33N5O/c1-20-10-12-21(13-11-20)27-24(26)28-25(14-6-3-7-15-25)23(31)30-18-16-29(17-19-30)22-8-4-2-5-9-22/h2,4-5,8-13H,3,6-7,14-19H2,1H3,(H3,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.24E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kansas University Specialized Chemistry Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His6-tagged ERAP1 expressed in baculovirus infected BTA-TN-5B1-4 insect cells using WRCYEKMALK as substrat...				J Med Chem 63: 103-121 (2020) Article DOI: 10.1021/acs.jmedchem.9b00293 BindingDB Entry DOI: 10.7270/Q2DN48D3
					More data for this Ligand-Target Pair
Endoplasmic reticulum aminopeptidase 1 (Homo sapiens (Human))	BDBM50519954 (CHEMBL4434818) Show SMILES Cc1ccc(NC(=N)NC2(CCCCC2)C(=O)N2CCN(CC2)c2ccccc2)cc1 Show InChI InChI=1S/C25H33N5O/c1-20-10-12-21(13-11-20)27-24(26)28-25(14-6-3-7-15-25)23(31)30-18-16-29(17-19-30)22-8-4-2-5-9-22/h2,4-5,8-13H,3,6-7,14-19H2,1H3,(H3,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kansas University Specialized Chemistry Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His6-tagged ERAP1 expressed in baculovirus infected BTA-TN-5B1-4 insect cells using L-AMC as substrate mea...				J Med Chem 63: 103-121 (2020) Article DOI: 10.1021/acs.jmedchem.9b00293 BindingDB Entry DOI: 10.7270/Q2DN48D3
					More data for this Ligand-Target Pair
Endoplasmic reticulum aminopeptidase 1 (Homo sapiens (Human))	BDBM50519954 (CHEMBL4434818) Show SMILES Cc1ccc(NC(=N)NC2(CCCCC2)C(=O)N2CCN(CC2)c2ccccc2)cc1 Show InChI InChI=1S/C25H33N5O/c1-20-10-12-21(13-11-20)27-24(26)28-25(14-6-3-7-15-25)23(31)30-18-16-29(17-19-30)22-8-4-2-5-9-22/h2,4-5,8-13H,3,6-7,14-19H2,1H3,(H3,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kansas University Specialized Chemistry Center Curated by ChEMBL					Assay Description Inhibition of ERAP1 in human HeLa cells stably expressing H-2 Kb infected with vaccinia virus containing ss-LEQLE-SIINFEKL epitope assessed as suppre...				J Med Chem 63: 103-121 (2020) Article DOI: 10.1021/acs.jmedchem.9b00293 BindingDB Entry DOI: 10.7270/Q2DN48D3
					More data for this Ligand-Target Pair