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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Endoplasmic reticulum aminopeptidase 2' and Ligand = 'BDBM50519957'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Endoplasmic reticulum aminopeptidase 2


(Homo sapiens (Human))		BDBM50519957
PNG
(CHEMBL4586487)
Show SMILES CC(=O)N1CCN(CC1)C(=O)C1(CCCCC1)NC(=N)Nc1ccc(Cl)cc1
Show InChI InChI=1S/C20H28ClN5O2/c1-15(27)25-11-13-26(14-12-25)18(28)20(9-3-2-4-10-20)24-19(22)23-17-7-5-16(21)6-8-17/h5-8H,2-4,9-14H2,1H3,(H3,22,23,24)
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a



Kansas University Specialized Chemistry Center

Curated by ChEMBL


Assay Description
Inhibition of recombinant human C-terminal His6-tagged ERAP2 expressed in baculovirus infected BTA-TN-5B1-4 insect cells using R-AMC as substrate mea...

J Med Chem 63: 103-121 (2020)


Article DOI: 10.1021/acs.jmedchem.9b00293
BindingDB Entry DOI: 10.7270/Q2DN48D3
More data for this
Ligand-Target Pair