Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Endothelial lipase' and Ligand = 'BDBM123907'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM123907 (US8754113, I-3-48) Show SMILES O=C(Cc1nnc(Cc2nc3ccc(cc3s2)C2=CCOCC2)o1)NC1(CC1)C#N |t:19| Show InChI InChI=1S/C21H19N5O3S/c22-12-21(5-6-21)24-17(27)10-18-25-26-19(29-18)11-20-23-15-2-1-14(9-16(15)30-20)13-3-7-28-8-4-13/h1-3,9H,4-8,10-11H2,(H,24,27)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	37
Shionogi & Co., Ltd. US Patent					Assay Description After the present compound dissolved in DMSO was added to become 0.5% DMSO to the reaction buffer consisting of 20 mM tris hydrochloric acid (pH7.4),...				US Patent US8754113 (2014) BindingDB Entry DOI: 10.7270/Q27D2SVD
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