Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Endothelial lipase' and Ligand = 'BDBM187343'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM187343 (US9169240, 82) Show SMILES FC(F)Oc1ccc(cc1)-c1ccc2nc(sc2c1)C(=O)c1nnc(N[C@H]2CCNC2=O)o1 |r| Show InChI InChI=1S/C21H15F2N5O4S/c22-20(23)31-12-4-1-10(2-5-12)11-3-6-13-15(9-11)33-19(25-13)16(29)18-27-28-21(32-18)26-14-7-8-24-17(14)30/h1-6,9,14,20H,7-8H2,(H,24,30)(H,26,28)/t14-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	8.0	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The enzymatic assay was measured using white, opaque 96-well half area plates. Each well contained 60 μL of assay buffer (50 mM HEPES pH 8.0, 50...				US Patent US9169240 (2015) BindingDB Entry DOI: 10.7270/Q2W66JK8
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