Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Endothelial lipase' and Ligand = 'BDBM204993'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM204993 (US9249096, 1) Show SMILES CN1CC(C(=O)NCCc2ccc(Cl)c(Cl)c2)=C(O)C1=O |t:17| Show InChI InChI=1S/C14H14Cl2N2O3/c1-18-7-9(12(19)14(18)21)13(20)17-5-4-8-2-3-10(15)11(16)6-8/h2-3,6,19H,4-5,7H2,1H3,(H,17,20)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	296	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of endothelial lipase in human HT1080 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by substrat...				ACS Med Chem Lett 9: 673-678 (2018) Article DOI: 10.1021/acsmedchemlett.8b00138 BindingDB Entry DOI: 10.7270/Q2JS9T2R
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM204993 (US9249096, 1) Show SMILES CN1CC(C(=O)NCCc2ccc(Cl)c(Cl)c2)=C(O)C1=O |t:17| Show InChI InChI=1S/C14H14Cl2N2O3/c1-18-7-9(12(19)14(18)21)13(20)17-5-4-8-2-3-10(15)11(16)6-8/h2-3,6,19H,4-5,7H2,1H3,(H,17,20)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	528	n/a	n/a	n/a	n/a	8.0	37
Bristol-Myers Squibb Company US Patent					Assay Description The enzymatic assay was measured using white, opaque 96-well half area plates. Each well contained 60 uL of assay buffer (50 mM HEPES pH 8.0, 50 mM N...				US Patent US9249096 (2016) BindingDB Entry DOI: 10.7270/Q2RX99X0
					More data for this Ligand-Target Pair