Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Endothelial lipase' and Ligand = 'BDBM205116'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM205116 (US9249096, 166) Show SMILES CN1CC(C(=O)NCCCc2ccccc2)=C(O)C1=O |t:16| Show InChI InChI=1S/C15H18N2O3/c1-17-10-12(13(18)15(17)20)14(19)16-9-5-8-11-6-3-2-4-7-11/h2-4,6-7,18H,5,8-10H2,1H3,(H,16,19)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.83E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of endothelial lipase in human HT1080 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by substrat...				ACS Med Chem Lett 9: 673-678 (2018) Article DOI: 10.1021/acsmedchemlett.8b00138 BindingDB Entry DOI: 10.7270/Q2JS9T2R
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM205116 (US9249096, 166) Show SMILES CN1CC(C(=O)NCCCc2ccccc2)=C(O)C1=O |t:16| Show InChI InChI=1S/C15H18N2O3/c1-17-10-12(13(18)15(17)20)14(19)16-9-5-8-11-6-3-2-4-7-11/h2-4,6-7,18H,5,8-10H2,1H3,(H,16,19)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.45E+3	n/a	n/a	n/a	n/a	8.0	37
Bristol-Myers Squibb Company US Patent					Assay Description The enzymatic assay was measured using white, opaque 96-well half area plates. Each well contained 60 uL of assay buffer (50 mM HEPES pH 8.0, 50 mM N...				US Patent US9249096 (2016) BindingDB Entry DOI: 10.7270/Q2RX99X0
					More data for this Ligand-Target Pair