Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Endothelial lipase' and Ligand = 'BDBM50521227'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM50521227 (CHEMBL4473964) Show SMILES COC(=O)Nc1ccc(cc1)-c1ccc2nc(sc2c1)C(c1nnc(CNS(N)(=O)=O)o1)S(=O)(=O)Cc1ccccc1 Show InChI InChI=1S/C26H24N6O7S3/c1-38-26(33)29-19-10-7-17(8-11-19)18-9-12-20-21(13-18)40-25(30-20)23(41(34,35)15-16-5-3-2-4-6-16)24-32-31-22(39-24)14-28-42(27,36)37/h2-13,23,28H,14-15H2,1H3,(H,29,33)(H2,27,36,37)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of endothelial lipase in human HT1080 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by substrat...				ACS Med Chem Lett 9: 1263-1268 (2018) Article DOI: 10.1021/acsmedchemlett.8b00424 BindingDB Entry DOI: 10.7270/Q2TF01QC
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50521227 (CHEMBL4473964) Show SMILES COC(=O)Nc1ccc(cc1)-c1ccc2nc(sc2c1)C(c1nnc(CNS(N)(=O)=O)o1)S(=O)(=O)Cc1ccccc1 Show InChI InChI=1S/C26H24N6O7S3/c1-38-26(33)29-19-10-7-17(8-11-19)18-9-12-20-21(13-18)40-25(30-20)23(41(34,35)15-16-5-3-2-4-6-16)24-32-31-22(39-24)14-28-42(27,36)37/h2-13,23,28H,14-15H2,1H3,(H,29,33)(H2,27,36,37)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of endothelial lipase in human HT1080 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by substrat...				ACS Med Chem Lett 9: 1263-1268 (2018) Article DOI: 10.1021/acsmedchemlett.8b00424 BindingDB Entry DOI: 10.7270/Q2TF01QC
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50521227 (CHEMBL4473964) Show SMILES COC(=O)Nc1ccc(cc1)-c1ccc2nc(sc2c1)C(c1nnc(CNS(N)(=O)=O)o1)S(=O)(=O)Cc1ccccc1 Show InChI InChI=1S/C26H24N6O7S3/c1-38-26(33)29-19-10-7-17(8-11-19)18-9-12-20-21(13-18)40-25(30-20)23(41(34,35)15-16-5-3-2-4-6-16)24-32-31-22(39-24)14-28-42(27,36)37/h2-13,23,28H,14-15H2,1H3,(H,29,33)(H2,27,36,37)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of endothelial lipase in human HT1080 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by substrat...				ACS Med Chem Lett 9: 1263-1268 (2018) Article DOI: 10.1021/acsmedchemlett.8b00424 BindingDB Entry DOI: 10.7270/Q2TF01QC
					More data for this Ligand-Target Pair