Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Endothelial lipase' and Ligand = 'BDBM50521234'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM50521234 (CHEMBL4536805) Show SMILES CC1(Cc2nnc(o2)C(c2nc3ccc(cc3s2)-c2ccccc2)S(C)(=O)=O)NC(=O)NC1=O Show InChI InChI=1S/C22H19N5O5S2/c1-22(20(28)24-21(29)25-22)11-16-26-27-18(32-16)17(34(2,30)31)19-23-14-9-8-13(10-15(14)33-19)12-6-4-3-5-7-12/h3-10,17H,11H2,1-2H3,(H2,24,25,28,29)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of endothelial lipase in human HT1080 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by substrat...				ACS Med Chem Lett 9: 1263-1268 (2018) Article DOI: 10.1021/acsmedchemlett.8b00424 BindingDB Entry DOI: 10.7270/Q2TF01QC
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50521234 (CHEMBL4536805) Show SMILES CC1(Cc2nnc(o2)C(c2nc3ccc(cc3s2)-c2ccccc2)S(C)(=O)=O)NC(=O)NC1=O Show InChI InChI=1S/C22H19N5O5S2/c1-22(20(28)24-21(29)25-22)11-16-26-27-18(32-16)17(34(2,30)31)19-23-14-9-8-13(10-15(14)33-19)12-6-4-3-5-7-12/h3-10,17H,11H2,1-2H3,(H2,24,25,28,29)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of endothelial lipase in human HT1080 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by substrat...				ACS Med Chem Lett 9: 1263-1268 (2018) Article DOI: 10.1021/acsmedchemlett.8b00424 BindingDB Entry DOI: 10.7270/Q2TF01QC
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50521234 (CHEMBL4536805) Show SMILES CC1(Cc2nnc(o2)C(c2nc3ccc(cc3s2)-c2ccccc2)S(C)(=O)=O)NC(=O)NC1=O Show InChI InChI=1S/C22H19N5O5S2/c1-22(20(28)24-21(29)25-22)11-16-26-27-18(32-16)17(34(2,30)31)19-23-14-9-8-13(10-15(14)33-19)12-6-4-3-5-7-12/h3-10,17H,11H2,1-2H3,(H2,24,25,28,29)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of endothelial lipase in human HT1080 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by substrat...				ACS Med Chem Lett 9: 1263-1268 (2018) Article DOI: 10.1021/acsmedchemlett.8b00424 BindingDB Entry DOI: 10.7270/Q2TF01QC
					More data for this Ligand-Target Pair