Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Endothelin receptor type B' and Ligand = 'BDBM50034258'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelin receptor type B (RAT)	BDBM50034258 (3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-hydroxy-5-p-tol...) Show SMILES Cc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccccc1)c1ccc2OCOc2c1 |c:13| Show InChI InChI=1S/C25H20O5/c1-16-7-10-19(11-8-16)25(27)20(13-17-5-3-2-4-6-17)23(24(26)30-25)18-9-12-21-22(14-18)29-15-28-21/h2-12,14,27H,13,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Tested for antagonistic activity against Endothelin B receptor in the rat cerebellum.				J Med Chem 38: 1259-63 (1995) BindingDB Entry DOI: 10.7270/Q2WH2P1B
					More data for this Ligand-Target Pair
Endothelin receptor type B (Homo sapiens (Human))	BDBM50034258 (3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-hydroxy-5-p-tol...) Show SMILES Cc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccccc1)c1ccc2OCOc2c1 |c:13| Show InChI InChI=1S/C25H20O5/c1-16-7-10-19(11-8-16)25(27)20(13-17-5-3-2-4-6-17)23(24(26)30-25)18-9-12-21-22(14-18)29-15-28-21/h2-12,14,27H,13,15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity against human cloned Endothelin B receptor expressed in CHO-K1 cells				J Med Chem 40: 1063-74 (1997) Article DOI: 10.1021/jm9606507 BindingDB Entry DOI: 10.7270/Q27P8XG5
					More data for this Ligand-Target Pair
Endothelin receptor type B (Homo sapiens (Human))	BDBM50034258 (3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-hydroxy-5-p-tol...) Show SMILES Cc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccccc1)c1ccc2OCOc2c1 |c:13| Show InChI InChI=1S/C25H20O5/c1-16-7-10-19(11-8-16)25(27)20(13-17-5-3-2-4-6-17)23(24(26)30-25)18-9-12-21-22(14-18)29-15-28-21/h2-12,14,27H,13,15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Tested for antagonistic activity against Endothelin B receptor in human (CHO expressed).				J Med Chem 38: 1259-63 (1995) BindingDB Entry DOI: 10.7270/Q2WH2P1B
					More data for this Ligand-Target Pair